MACDERMOTT, John Clarke (Baron MacDermott) (1896-1979): Photocopies of extracts from MacDermott's autobiography, 'An enriching life', privately printed in 1979, primarily concerning the death of his brother in France, Jan 1916, MacDermott's work in shell shop at Harland and Wolff Ltd, 1916, his experience of the Easter Rising, Dublin, Apr 1916, his military training in Belfast and the UK, 1916-1917, his service in France, Belgium and Germany, including the Battle of the Lys, Apr 1918, and the second Battle of the Marne, Jul-Aug 1918, his legal training, 1919-1921, and his reading of FM Sir Henry Wilson...his life and diaries by Sir Charles Edward Callwell (Cassell and Co, London, 1927) and Revolt in the Desert by Thomas Edward Lawrence (later Shaw) (Jonathon Cape, London, 1927) and also including a tribute by to MacDermott Lord Robert Lynd Erskine Lowry, Baron Lowry, Lord Chief Justice of Northern Ireland. [Text] [View with Perseus links] (1.66)
Unknown; Epitome of <i>A Commentary on Antoninus, his Itinerary</i> by William Burton: Manuscript copy of <i>An Epitome of Mr. Burtons Commentary on the British part of Antoninus his Itinerary</i>, 1666. The title-page is decorated with fleurs-de-lys in red, a lion rampant and various inscriptions. There are also alphabetical tables to the text, and folios 19-61 are numbered as 1-85. <br>Burton's Commentary was published in 1658, but this Epitome was never published. [Text] [View with Perseus links] (1.15)
FM Douglas Haig, 1st Earl Haig, 1914-1919; Microform: FM Earl Haig: autograph diaries and letters home to his wife, 1914-1919: Microfilmed copies of the manuscript diaries of FM Douglas Haig, 1st Earl Haig, 1914-1919, and letters to his wife Dorothy Vivian Haig, Aug 1914-Mar 1919. Included in the papers are passages relating to the formation and composition of the British Expeditionary Force (BEF), under the command of FM Sir John Denton Pinkstone French, July 1914; Haig's reaction, as General Officer Commanding 1 Army, British Expeditionary Forces in France and Flanders (BEF), to the British retreat following the First Battle of Ypres, Dec 1914; plans for the British offensive at Loos, Jul-Sep 1915; correspondence with FM Horatio Herbert Kitchener, 1st Earl Kitchener of Khartoum and Broome, relating to the French's command of the Artois-Loos Offensive, Sep 1915; correspondence with Gen Sir William (Robert) Robertson, Chief of General Staff, relating to the proposed increase of British fighting forces in France, Oct 1915; the dismissal of French and the succession of Haig as Commander-in-Chief, British Armies in France, Dec 1915; Haig's recommendations for Lt Gen Sir Henry Seymour Rawlinson as his successor as General Officer Commanding 1 Army, Dec 1915; correspondence with Rt Hon Richard Burdon Haldane, 1st Viscount Haldane of Cloan, relating to Haig's appointment to Commander-in-Chief, British Armies in France, Dec 1915; orders from Kitchener to Haig concerning proposed Allied offensives in France and liaison with French Gen Joseph Jacques Cesaire Joffre, Jan 1916; letter from Robertson, Chief of the Imperial General Staff, to Haig relating to possible British offensives in the Balkans, Iraq and Germany, Jan 1916; discussions with Gen Sir Herbert Charles Onslow Plumer, General Officer Commanding 2 Army, British Armies in France, relating to possible British offensives at Ypres, Jan 1916; the German offensive at Verdun and the resultant requests by the French General Staff for a British relief offensive from Ypres to Armentieres, Feb 1916; alleged incompetence within 2 Canadian Div command, Apr 1916; discussions with Robertson, Maj Gen Sir Launcelot Edward Kiggell, Chief of General Staff to British Armies in France, and Brig Gen Richard Harte Keatinge Butler, Deputy Chief of General Staff to the British Armies in France, relating to the proposed offensive at the Somme (Jul-Nov 1916), May 1916; Haig's instructions to Rawlinson, General Officer Commanding 4 Army, British Armies in France, regarding the proposed limited infantry attack on the Somme, Jun 1916; Haig's reaction to British Cabinet criticism of British casualty figures during the Somme offensive, Jul 1916; analysis of German casualty figures during the Somme offensive, Nov 1916; Haig's reaction to replacement of Rt Hon Herbert Henry Asquith, Prime Minister of Great Britain and First Lord of the Treasury, with Rt Hon David Lloyd George, 1916; Haig's reaction to replacement of Joffre as Commander-in-Chief of the French Armies with French Gen Robert Georges Nivelle, 1916; Haig's promotion to FM, 1917; supplies and manpower required for proposed British and French combined Nivelle offensive, 1917; Haig's reaction to German withdrawal to defensive positions along the Hindenburg Line, 1917; Haig's reaction to Calais Conference proceedings, in which combined British and French command council is proposed, 1917; Haig and Robertson' s veto of Gen Sir Henry Hughes Wilson as proposed British Chief of Staff liaison to Nivelle's Headquarters; the re-organisation of the Allied command structure as a result of the Calais Agreement, 1917; the failed French offensive at Aisne, Apr 1917; plans for the Passchendaele Campaign (Jul-Nov 1917) and the choice of General Hubert (de la Poer) Gough's 5 Army as the main British assaulting force, 1917; Haig's fears of a French civil and military collapse, 1917; conference with Gen John Joseph Pershing, Commander-in-Chief American Expeditionary Forces in Europe, Jul 1917; severe criticism levelled at Haig concerning his command of the Passchendaele Campaign, Jul-Nov 1917; Haig's reaction to the establishment of the Inter-Allied War Supreme War Council at Versailles, France, and the posting of Wilson as its British representative, 1918; Robertson's replacement as Chief of the Imperial General Staff by Wilson, 1918; the shortage of British military reserves in France, 1918; the failure of the German 'spring offensives' at Arras, France, Lys, Belgium, and Aisne, France, Mar-May 1918; straining relations between Haig and FM Ferdinand Foch, Marshal of France and Generalissimo of the Allied Forces, France, 1918; the Battle of Amiens, Aug 1918; the terms of the armistice, Nov 1918; perceptions of the Paris Peace Conference and the resultant Treaty of Versailles, 1919. [Text] [View with Perseus links] (0.80)
Bennett, Vicki J, Simmons, Mark A; Analysis of fluorescently labeled substance P analogs: binding, imaging and receptor activation: (in English) AbstractBackgroundSubstance P (SP) is a peptide neurotransmitter found in central and peripheral nerves. SP is involved in the control of smooth muscle, inflammation and nociception. The amino acid sequence of SP is Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2. Five different forms of fluorescently labeled SP have recently been synthesized, in which Alexa 488, BODIPY Fl, fluorescein, Oregon Green 488 or tetramethylrhodamine has been covalently linked to SP at Lys3. Here, these novel analogs are characterized as to their ligand binding, receptor activation and fluorescence labeling properties.ResultsCompetition binding studies, using radiolabeled [125I] SP, revealed that all of the labeled forms of SP, except for Alexa 488-SP, effectively competed with radiolabeled SP for binding at the rat SP receptor. With the exception of Alexa 488-SP, all of the SP analogs produced Ca++ elevations and fluorescence labeling of the SP receptor expressed in Chinese hamster ovary cells. In SP-responsive neurons, BODIPY Fl-SP and Oregon Green 488-SP were as effective as unlabeled SP in producing a reduction of the M-type K+ current. Fluorescein-SP produced variable results, while tetramethylrhodamine-SP was less potent and Alexa 488-SP was less effective on intact neurons.ConclusionsThe above results show that fluorescent labeling of SP altered the biological activity and the binding properties of the parent peptide. Oregon Green 488 and BODIPY FL-SP are the most useful fluorophores for labeling SP without affecting its biological activity. Given these results, these probes can now be utilized in further investigations of the mechanisms of SPR function, including receptor localization, internalization and recycling. [Text] [View with Perseus links] (1.40)
Christophe Terzian, Alain Pelisson, Alain Bucheton; Evolution and phylogeny of insect endogenous retroviruses: (in English) AbstractBackgroundThe genome of invertebrates is rich in retroelements which are structurally reminiscent of the retroviruses of vertebrates. Those containing three open reading frames (ORFs), including an env-like gene, may well be considered as endogenous retroviruses. Further support to this similarity has been provided by the ability of the env-like gene of DmeGypV (the Gypsy endogenous retrovirus of Drosophila melanogaster) to promote infection of Drosophila cells by a pseudotyped vertebrate retrovirus vector.ResultsTo gain insights into their evolutionary story, a sample of thirteen insect endogenous retroviruses, which represents the largest sample analysed until now, was studied by computer-assisted comparison of the translated products of their gag, pol and env genes, as well as their LTR structural features. We found that the three phylogenetic trees based respectively on Gag, Pol and Env common motifs are congruent, which suggest a monophyletic origin for these elements.ConclusionsWe showed that most of the insect endogenous retroviruses belong to a major clade group which can be further divided into two main subgroups which also differ by the sequence of their primer binding sites (PBS). We propose to name IERV-K and IERV-S these two major subgroups of Insect Endogenous Retro Viruses (or Insect ERrantiVirus, according to the ICTV nomenclature) which respectively use Lys and Ser tRNAs to prime reverse transcription. [Text] [View with Perseus links] (1.15)
... ; The fission yeast COP9/signalosome is involved in cullin modification by ubiquitin-related Ned8p: (in English) AbstractBackgroundThe function of the fission yeast cullins Pcu1p and Pcu4p requires modification by the ubiquitin-related peptide Ned8p. A recent report by Lyapina et al. shows that the COP9/signalosome (CSN), a multifunctional eight subunit complex, regulates Ned8p modification of Pcu1p. Disruption of caa1/csn1, which encodes subunit 1 of the putative S. pombe CSN, results in accumulation of Pcu1p exclusively in the modified form. However, it remained unclear whether this reflects global control of all cullins by the entire CSN complex.ResultsWe demonstrate that multiple CSN subunits control Ned8p modification of Pcu3p, another fission yeast cullin, which, in complex with the RING domain protein Pip1p, forms a ubiquitin ligase that functions in cellular stress response. Pcu3p is modified by Ned8p on Lys 729 and accumulates exclusively in the neddylated form in cells lacking the CSN subunits 1, 3, 4, and 5. These CSN subunits co-elute with Pcu3p in gel filtration fractions corresponding to ∼ 550 kDa and specifically bind both native and Ned8p-modified Pcu3p in vivo. While CSN does not influence the subcellular localization of Pcu3p, Pcu3p-associated in vitro ubiquitin ligase activity is stimulated in the absence of CSN.ConclusionsTaken together, our data suggest that CSN is a global regulator of Ned8p modification of multiple cullins and potentially other proteins involved in cellular regulation. [Text] [View with Perseus links] (0.80)
Envelope - Ethnic Scout & Guide Association Victoria: for print and a printed logo u.l. The logo is within a circle made from the Association's name and consists of a fleur-de-lys like symbol in olive ink. The reverse has self adhesive flaps; the lower flap is printed. [Text] (5.20)
COLLECTOR: NICHOLSON, SIR CHARLES, 1858; COLLECTOR: NICHOLSON, SIR CHARLES, 1858; (in English) Length: 6.6, Width: 4.1 cm (?) / 1286 CHICHESTER CITY SEAL; EAGLE, FLEUR-DE-LYS, BORDER MOTTO / COLLECTOR: NICHOLSON, SIR CHARLES, 1858; NICHOLSON MUS.TRS.1984 [Text] (2.59)
Medallion - Australian International Exhibition: The box is imprinted in gold on top. A (fleur de lys) E / Royal (Commission) / Australian International Exhibition. The inside top of the box is stamped in gold with a crown inside an inscription V??ON Gent Street, London. Obverse on medallion around outside is Australian International Exhibition Sydney 1879 -*Inscription [Text] (1.90)
De Vries, William Levering,--1865-1937.; Ethopoiia.--A rhetorical study of the types of character in the orations of Lysias, by William Levering Devries.: Thesis--Johns Hopkins university, 1892., Bibliography: p. [7] [Text] (10.12)
Williams, Debra Jackson.; Une eI?itude de la dialectique de l'amour dans Le Lys dans la valleI?ie de Balzac et dans VolupteI?i de Sainte-Beuve /--by Debra Jackson Williams.: Director of this thesis, Dr. Arthur R. Evans, Jr., Dept. of Romance Languages., Thesis (M.A.)--Emory University., Bibliography: leaves [76]-77. [Text] (7.44)
Friedman, Dianne de Lys.; The prenatal and perinatal histories of ten reading disabled children.--A project based upon an independent investigation.: Typewritten., Thesis (M.S.) - Smith College School for Social Work, 1974., Bibliography: a?IJN.98-100. [Text] (3.83)
Radcliffe, John Scott; The Use of Steered Ileo-cecal Valve Cannulated Pigs to Evaluate the Effects of Adding Phytase or Beta-mannanase to the Diet on Amino Acid, Mineral and Energy Utilization: D. M. Denbow, R. S. Pleasant, J. P. Fontenot, B. A. Davis, A. F. Harper; (in English) Forty-six barrows fitted with steered ileo-cecal valve cannulas were used in four experiments to evaluate the effects of supplementing swine diets with microbial phytase or beta-mannanase on the apparent ileal (AID) and/or apparent total tract digestibility (ATTD) of amino acids, N, Ca, P, DM and energy. In Exp. 1, the addition of phytase to low CP corn-soybean meal based diets increased the AID of Ca (P < .01), P (P < .001), and all amino acids (P < .10) measured except Leu, Ser, Pro, Met, His and Tyr. In Exp. 2, the addition of microbial phytase to corn-soybean meal, corn-soybean meal-wheat middlings, or corn-soybean meal-meat and bone meal based diets resulted in increased AID of Ca and P, but had no effect (P > .1) on amino acid digestibilities. Diet type affected all digestibility measurements, but did not affect the efficacy of supplemental phytase. In Exp. 3, the addition of microbial phytase to corn-wheat-soybean meal, corn-wheat-cannola, or sorghum-corn-soybean meal based diets led to an increased ( P <.05) AID of P, Asp, Thr, Ser, Ala, Tyr, Phe, Lys and Arg. In Exp. 4, the addition of beta-mannanase to corn-soybean meal based swine diets led to an increased AID of DM and ATTD of energy. In addition, the AID of all amino acids measured were increased numerically, with many of these values approaching significance. The results of these studies demonstrate that supplementing pig diets with phytase or beta-mannanase, results in an increased digestibility of certain dietary components due to the breakdown of anti-nutritive compounds in the diet. [Text] [View with Perseus links] (1.09)